Airway Bistability Is Modulated by Smooth Muscle Dynamics and Length-Tension Characteristics
نویسندگان
چکیده
منابع مشابه
Selected contribution: effect of chronic passive length change on airway smooth muscle length-tension relationship.
The ability of rabbit trachealis to undergo plastic adaptation to chronic shortening or lengthening was assessed by setting the muscle preparations at three lengths for 24 h in relaxed state: a reference length in which applied force was approximately 1-2% of maximal active force (P(o)) and lengths considerably shorter and longer than the reference. Passive and active length-tension (L-T) curve...
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BACKGROUND Airway smooth muscle (ASM) hyperplasia and mast cell localization within the ASM bundle are important features of asthma. The cause of this increased ASM mass is uncertain and whether it is a consequence of ASM-mast cell interactions is unknown. OBJECTIVE We sought to investigate ASM proliferation and survival in asthma and the effects of co-culture with mast cells. METHODS Prima...
متن کاملPlasticity in Skeletal, Cardiac, and Smooth Muscle Selected Contribution: Effect of chronic passive length change on airway smooth muscle length-tension relationship
Wang, Lu, Peter D. Paré, and Chun Y. Seow. Selected Contribution: Effect of chronic passive length change on airway smooth muscle length-tension relationship. J Appl Physiol 90: 734–740, 2001.—The ability of rabbit trachealis to undergo plastic adaptation to chronic shortening or lengthening was assessed by setting the muscle preparations at three lengths for 24 h in relaxed state: a reference ...
متن کاملAdjustable passive length-tension curve in rabbit detrusor smooth muscle.
Until the 1990s, the passive and active length-tension (L-T) relationships of smooth muscle were believed to be static, with a single passive force value and a single maximum active force value for each muscle length. However, recent studies have demonstrated that the active L-T relationship in airway smooth muscle is dynamic and adapts to length changes over a period of time. Furthermore, our ...
متن کاملPoint: airway smooth muscle is useful.
Some ideas just sit and stare at you. Here is one that has bothered me for a year or so. It is hard for me to regard smooth muscles as vestigial (3, 4) and they can not be solely mean-spirited, so they probably have useful function. With no library and no computer, I just fell back on Intelligent Design Un-Googled. And off I went job hunting on behalf of airway smooth muscles. Do they manage th...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2016
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2016.10.007